CCDC184

Across TCGA patient cohorts, CCDC184 mutation is significantly associated with the RNA expression of many other genes, with 1,701 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC184-associated genes across cancer lineages are RPL23AP90, MRPL2P1, and SHMT1P1. Each is linked with CCDC184 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC184-to-partner and partner-to-CCDC184 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP90 grouped by CCDC184-low versus CCDC184-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC184→partner) and Y-score (partner→CCDC184) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPL23AP90 →	+0.243	+3.842	.008	.005	3	2
LIHC	MRPL2P1 →	+0.060	+3.589	<.001	.006	3	2
UCEC	SHMT1P1 →	+0.142	+2.223	.007	.004	3	2
UCEC	CRYBB2P1 →	+0.505	+2.436	.001	.002	3	1
UCEC	PACSIN2 →	+0.572	+2.606	<.001	.005	3	1
UCEC	AP1B1 →	+0.530	+2.593	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,701 associations by consensus.

RPL23AP90 by CCDC184 expression — LIHC

Explore this box plot interactively →