CCDC184

Across TCGA patient cohorts, CCDC184 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC184-associated genes across cancer lineages are ATM, EGFR_pY1068, and eIF4E. Each is linked with CCDC184 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC184-to-partner and partner-to-CCDC184 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CCDC184-low versus CCDC184-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC184→partner) and Y-score (partner→CCDC184) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.626	-3.459	.001	.005	3	2
UCEC	EGFR_pY1068 →	-0.347	-3.906	.001	<.001	3	1
UCEC	eIF4E →	+0.239	+3.584	.009	.002	3	1
UCEC	A-Raf_pS299 →	-0.142	-2.459	.006	.019	3	1
UCEC	GAPDH →	+0.557	+2.115	.017	.019	3	1
UCEC	GATA6 →	-0.187	-2.108	.005	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ATM by CCDC184 expression — UCEC

Explore this box plot interactively →