Across TCGA patient cohorts, CCDC183 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC183-associated genes across cancer lineages are p53, p62 Lck ligand, and PCNA. Each is linked with CCDC183 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC183-to-partner and partner-to-CCDC183 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC183→partner) and Y-score (partner→CCDC183) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p53 →	-0.381	-3.459	.024	.005	3	1
UCEC	p62 Lck ligand →	+0.315	+2.807	.027	.003	3	1
UCEC	PCNA →	+0.232	+2.459	.014	.019	3	1
UCEC	S6_pS240_S244 →	+0.376	+3.000	.034	.036	3	1
UCEC	ATM →	-0.408	-2.321	.039	.034	3	1
UCEC	Di-Ras3 →	-0.164	-2.115	.011	.019	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

CCDC183 survival (RNA) · tumor vs normal (RNA) · all CCDC183 data types