Across TCGA pan-cancer cohorts, CCDC180 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCDC180 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher CCDC180 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated CCDC180 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

ESCA and LUAD are the cancer types where CCDC180 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	III,IV	1.000	0.269	.015	29	view →
LUAD	OS	Median	All	0.224	0.675	.003	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CCDC180 tumor-vs-normal RNA expression · all CCDC180 data types