CCDC180

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC180 mutation is significantly associated with the RNA expression of many other genes, with 282 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC180-associated genes across cancer lineages are ELOA3DP, OR1P1, and HS3ST2. Each is linked with CCDC180 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC180-to-partner and partner-to-CCDC180 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC180→partner) and Y-score (partner→CCDC180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaELOA3DP →+0.131+2.685<.001.00534
BLOOD_LeukemiaOR1P1 →+0.074+2.922<.001.00932
BLOOD_LeukemiaHS3ST2 →+0.464+3.339.001<.00132
BLOOD_LeukemiaHPCAL4 →+0.316+3.478<.001.00632
BLOOD_LeukemiaKSR2 →+0.319+3.955<.001<.00132
BLOOD_LeukemiaF11 →+0.058+2.855<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 282 associations by consensus.

Exploration