CCDC18

Across TCGA patient cohorts, CCDC18 protein abundance is significantly associated with the RNA expression of many other genes, with 5,395 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC18-associated genes across cancer lineages are ADGRG3, TJP3, and CORO2A. Each is linked with CCDC18 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC18-to-partner and partner-to-CCDC18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC18 versus ADGRG3 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC18→partner) and Y-score (partner→CCDC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADGRG3 →	+1.132	+1.045	<.001	<.001	3	3
LSCC	TJP3 →	+1.457	+0.827	.002	.004	3	2
GBM	CORO2A →	+1.055	+1.146	.002	<.001	3	2
BRCA	RASSF8 →	-1.052	-0.975	.002	.006	3	2
LSCC	SLPI →	+1.680	+0.938	<.001	<.001	3	2
UCEC	CDHR3 →	+1.303	+0.692	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,395 associations by consensus.

CCDC18 vs ADGRG3 — LSCC

Explore this scatter interactively →