CCDC18

Across TCGA patient cohorts, CCDC18 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,266 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC18-associated proteins across cancer lineages are ALS2_S1464, SLK_S189, and ZRANB2_S188. Each is linked with CCDC18 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC18-to-partner and partner-to-CCDC18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC18 versus ALS2_S1464 in HNSC, with a Pearson correlation of -0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC18→partner) and Y-score (partner→CCDC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALS2_S1464 →	-1.038	-0.993	<.001	<.001	3	3
HNSC	SLK_S189 →	-0.931	-1.113	<.001	<.001	3	3
LSCC	ZRANB2_S188 →	-1.520	-0.963	<.001	<.001	3	3
HNSC	FCHO2_S533 →	-1.059	-0.798	<.001	<.001	3	3
HNSC	NIPBL_S2658 →	-1.210	-0.882	<.001	<.001	3	3
UCEC	SASH3_S38 →	+1.013	+0.579	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,266 associations by consensus.

CCDC18 vs ALS2_S1464 — HNSC

Explore this scatter interactively →