CCDC18

Across TCGA cell cohorts, CCDC18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,078 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCDC18-associated GO terms across cancer lineages are Regulation of nuclear division, Double-strand break repair, and DNA recombination. Each is linked with CCDC18 in more than 18 cancer types. Because this analysis shows association rather than direction, both CCDC18-to-partner and partner-to-CCDC18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear division grouped by CCDC18-low versus CCDC18-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC18→partner) and Y-score (partner→CCDC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of nuclear division →	+0.121	+1.050	.006	.004	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.077	+1.486	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.069	+1.072	<.001	<.001	3	19
BONE	Spindle organization →	+0.098	+1.017	.001	.005	3	19
OESOPHAGUS	Mitotic spindle organization →	+0.139	+1.397	.003	.006	3	19
BONE	Chromosome segregation →	+0.132	+1.153	.007	.003	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,078 associations by consensus.

Regulation of nuclear division by CCDC18 expression — BONE

Explore this box plot interactively →