CCDC179

Across TCGA pan-cancer cohorts, CCDC179 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CCDC179 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CCDC179 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC179 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

UVM, LUSC, and DLBC are the cancer types where CCDC179 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Quartile	II,III,IV	0.370	0.655	<.001	117	view →
LUSC	DFS	Tertile	II,III,IV	0.568	0.743	.007	30	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	27	view →
LIHC	DFS	Tertile	All	0.406	0.563	.007	21	view →
THCA	DFS	Quartile	II,III,IV	0.510	0.810	.006	14	view →
KIRC	DFS	Tertile	IV	0.809	0.508	.025	12	view →
SCLC	DFS	Tertile	II,III,IV	1.000	0.349	.022	12	view →
SKCM	OS	Quartile	IV	0.133	0.621	.045	9	view →
KICH	OS	Tertile	III,IV	0.098	0.801	.004	6	view →
READ	DFS	Tertile	IV	0.318	0.660	.029	6	view →
PRAD	OS	Median	All	1.000	0.977	.014	6	view →
BRCA	DFS	Median	II,III,IV	0.959	0.928	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CCDC179–UVM (DFS)

Open the UVM breakdown →