CCDC175

Across TCGA pan-cancer cohorts, CCDC175 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCDC175 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CCDC175 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC175 expression acts as an unfavorable survival marker, although some lineages such as SCLC show a favorable association.

CESC and SCLC are the cancer types where CCDC175 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.088	0.543	.019	6	view →
SCLC	DFS	Median	All	1.000	0.264	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CCDC175–CESC (DFS)

Open the CESC breakdown →