CCDC175

Across TCGA patient cohorts, CCDC175 protein abundance is significantly associated with the RNA expression of many other genes, with 226 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCDC175-associated genes across cancer lineages are AQP9, DMXL2, and TMEM176B. Each is linked with CCDC175 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC175-to-partner and partner-to-CCDC175 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC175 versus AQP9 in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC175→partner) and Y-score (partner→CCDC175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AQP9 →	+1.171	+0.862	<.001	<.001	3	1
HNSC	DMXL2 →	+0.807	+1.008	.002	.005	3	1
HNSC	TMEM176B →	+1.305	+0.961	.006	<.001	3	1
HNSC	CSF3 →	+0.937	+0.657	.009	.007	3	1
HNSC	CLEC4A →	+0.506	+1.213	<.001	.001	3	1
HNSC	ASCC3 →	+0.437	+0.806	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 226 associations by consensus.

CCDC175 vs AQP9 — HNSC

Explore this scatter interactively →