CCDC175

Across TCGA patient cohorts, CCDC175 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible CCDC175-associated genes across cancer lineages are IFNA10, OR13C8, and KRTAP4-3. Each is linked with CCDC175 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC175-to-partner and partner-to-CCDC175 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA10 grouped by CCDC175-low versus CCDC175-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC175→partner) and Y-score (partner→CCDC175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	IFNA10 →	+0.116	+4.847	<.001	.009	3	1
SCLC	OR13C8 →	+0.114	+5.189	.004	.006	3	1
SCLC	KRTAP4-3 →	+0.087	+5.624	<.001	.003	3	1
UCEC	RNA5SP376 →	+0.556	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IFNA10 by CCDC175 expression — SCLC

Explore this box plot interactively →