CCDC174

Across TCGA patient cohorts, CCDC174 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,560 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCDC174-associated proteins across cancer lineages are NR2C2, TOP2B, and WDR48. Each is linked with CCDC174 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC174-to-partner and partner-to-CCDC174 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC174 versus NR2C2 in CCRCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC174→partner) and Y-score (partner→CCDC174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NR2C2 →	+0.316	+0.170	<.001	.004	3	6
OV	TOP2B →	+0.346	+0.479	.004	<.001	3	6
LSCC	WDR48 →	+0.202	+0.402	.001	.001	3	5
LUAD	TBC1D5 →	+0.221	+0.317	<.001	<.001	3	5
LSCC	VGLL4 →	+0.425	+0.360	<.001	<.001	3	5
UCEC	KIAA1143 →	+0.363	+0.543	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,560 associations by consensus.

CCDC174 vs NR2C2 — CCRCC

Explore this scatter interactively →