CCDC174

Across TCGA patient cohorts, CCDC174 protein abundance is significantly associated with the RNA expression of many other genes, with 7,042 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC174-associated genes across cancer lineages are KIF15, FANCD2, and TSEN2. Each is linked with CCDC174 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC174-to-partner and partner-to-CCDC174 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC174 versus KIF15 in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC174→partner) and Y-score (partner→CCDC174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIF15 →	+1.248	+0.362	<.001	<.001	3	5
GBM	FANCD2 →	+0.952	+0.372	<.001	<.001	3	4
BRCA	TSEN2 →	+0.474	+0.222	<.001	.004	3	4
HNSC	TEX21P →	+0.562	+0.284	<.001	.001	3	4
UCEC	DNA2 →	+0.592	+0.182	<.001	.001	3	4
GBM	RAD18 →	+0.585	+0.184	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,042 associations by consensus.

CCDC174 vs KIF15 — GBM

Explore this scatter interactively →