CCDC174

Across TCGA cell cohorts, CCDC174 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,542 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC174-associated GO terms across cancer lineages are Vesicle tethering, Regulation of mRNA stability, and Spliceosomal complex assembly. Each is linked with CCDC174 in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC174-to-partner and partner-to-CCDC174 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering grouped by CCDC174-low versus CCDC174-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC174→partner) and Y-score (partner→CCDC174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vesicle tethering →	+0.096	+0.893	<.001	<.001	3	12
KIDNEY	Regulation of mRNA stability →	+0.052	+0.742	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Spliceosomal complex assembly →	+0.113	+0.953	<.001	<.001	3	11
URINARY_TRACT	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.081	+0.844	<.001	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.047	+0.830	.008	.006	2	12
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.052	+0.790	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,542 associations by consensus.

Vesicle tethering by CCDC174 expression — STOMACH

Explore this box plot interactively →