CCDC174

Across TCGA cell cohorts, CCDC174 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC174-associated genes across cancer lineages are PNMA3 and CFHR2. Each is linked with CCDC174 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC174-to-partner and partner-to-CCDC174 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNMA3 grouped by CCDC174-low versus CCDC174-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC174→partner) and Y-score (partner→CCDC174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PNMA3 →	+0.143	+3.781	.002	.003	3	1
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PNMA3 by CCDC174 expression — LARGE_INTESTINE

Explore this box plot interactively →