CCDC172

Across TCGA patient cohorts, CCDC172 mutation is significantly associated with the RNA expression of many other genes, with 398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC172-associated genes across cancer lineages are RNA5SP349, RNU6-18P, and GYPB. Each is linked with CCDC172 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC172-to-partner and partner-to-CCDC172 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP349 grouped by CCDC172-low versus CCDC172-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC172→partner) and Y-score (partner→CCDC172) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP349 →	+0.203	+7.057	<.001	.009	3	3
BRCA	RNU6-18P →	+0.415	+4.986	<.001	.003	3	3
SCLC	GYPB →	+0.171	+4.774	<.001	<.001	3	2
SKCM	MIR7845 →	+0.236	+2.963	<.001	.001	3	2
UCEC	AKTIP →	+0.535	+3.364	.006	.005	3	2
UCEC	ALG10B →	+0.607	+3.364	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 398 associations by consensus.

RNA5SP349 by CCDC172 expression — BRCA

Explore this box plot interactively →