CCDC172

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC172 RNA expression is significantly associated with the mutation status of many other genes, with 159 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC172-associated genes across cancer lineages are SBF1, PLXNA2, and DROSHA. Each is linked with CCDC172 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC172-to-partner and partner-to-CCDC172 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SBF1 grouped by CCDC172-low versus CCDC172-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC172→partner) and Y-score (partner→CCDC172) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTSBF1 →+4.087+0.045.009<.00132
OESOPHAGUSPLXNA2 →+3.857+0.024.002.00332
KIDNEYDROSHA →+5.000+0.023.005<.00132
SKINGPT →+5.415+0.006.004<.00132
SKINCREBBP →+2.678+0.002.005<.00132
BLOOD_LymphomaPARP12 →+5.209+0.639.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

SBF1 by CCDC172 expression — URINARY_TRACT

Box plot of SBF1 in CCDC172-low vs CCDC172-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration