CCDC168

Across TCGA patient cohorts, CCDC168 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,084 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CCDC168-associated GO terms across cancer lineages are Regulation of centrosome cycle, Regulation of microtubule-based process, and Regulation of DNA-templated transcription initiation. Each is linked with CCDC168 in more than 30 cancer types. Because this analysis shows association rather than direction, both CCDC168-to-partner and partner-to-CCDC168 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome cycle grouped by CCDC168-low versus CCDC168-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC168→partner) and Y-score (partner→CCDC168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Regulation of centrosome cycle →	+0.101	+0.080	<.001	.009	2	31
ESCA	Regulation of microtubule-based process →	+0.071	+0.084	<.001	.001	3	30
DLBC	Regulation of DNA-templated transcription initiation →	+0.094	+0.099	.001	.008	1	31
DLBC	Microtubule organizing center organization →	+0.078	+0.085	.001	.003	2	30
STAD	Telomere organization →	+0.069	+0.051	<.001	<.001	3	29
SCLC	Negative regulation of gene expression, epigenetic →	+0.113	+0.150	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,084 associations by consensus.

Regulation of centrosome cycle by CCDC168 expression — DLBC

Explore this box plot interactively →