CCDC168

Across TCGA patient cohorts, CCDC168 mutation is significantly associated with the RNA expression of many other genes, with 4,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC168-associated genes across cancer lineages are H2AZ1, EEF1A1P40, and FADS2B. Each is linked with CCDC168 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC168-to-partner and partner-to-CCDC168 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2AZ1 grouped by CCDC168-low versus CCDC168-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC168→partner) and Y-score (partner→CCDC168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	H2AZ1 →	+0.574	+2.736	.004	.002	3	4
MESO	EEF1A1P40 →	+0.062	+4.772	<.001	.002	3	3
SARC	FADS2B →	+0.627	+3.775	<.001	<.001	3	3
SCLC	UBQLN1 →	+1.004	+3.243	.002	.003	3	3
LIHC	SNRPD3 →	+0.372	+1.855	.003	.005	3	3
LIHC	MRPS18C →	+0.309	+3.536	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,939 associations by consensus.

H2AZ1 by CCDC168 expression — LIHC

Explore this box plot interactively →