CCDC168

Across TCGA cell cohorts, CCDC168 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC168-associated GO terms across cancer lineages are Centrosome duplication, Mitotic chromosome condensation, and Microtubule organizing center organization. Each is linked with CCDC168 in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC168-to-partner and partner-to-CCDC168 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome duplication grouped by CCDC168-low versus CCDC168-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC168→partner) and Y-score (partner→CCDC168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Centrosome duplication →	+0.087	+0.086	<.001	.006	3	13
BONE	Mitotic chromosome condensation →	+0.123	+0.044	.003	<.001	3	12
BLOOD_Leukemia	Microtubule organizing center organization →	+0.061	+0.085	<.001	.001	2	12
BONE	Replication fork processing →	+0.098	+0.045	.008	.003	3	11
OESOPHAGUS	Ribosomal protein import into nucleus →	+0.088	+0.016	.007	.003	3	11
BONE	DNA replication-dependent chromatin assembly →	+0.130	+0.043	.004	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,139 associations by consensus.

Centrosome duplication by CCDC168 expression — BLOOD_Leukemia

Explore this box plot interactively →