CCDC168

Across TCGA cell cohorts, CCDC168 mutation is significantly associated with the RNA expression of many other genes, with 612 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC168-associated genes across cancer lineages are FCGR3B, OR56A4, and RTF2. Each is linked with CCDC168 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC168-to-partner and partner-to-CCDC168 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCGR3B grouped by CCDC168-low versus CCDC168-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC168→partner) and Y-score (partner→CCDC168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	FCGR3B →	+0.060	+3.514	.004	.008	3	3
LUNG_NSCLC_LUAD	OR56A4 →	+0.072	+2.555	.005	.006	3	2
LARGE_INTESTINE	RTF2 →	-0.562	-3.169	.001	.009	3	2
LARGE_INTESTINE	OOSP3 →	+0.057	+2.327	.004	.004	3	2
LUNG_NSCLC_LUSC	IFNA5 →	+0.076	+3.807	.003	.003	3	1
URINARY_TRACT	XPNPEP2 →	+0.029	+4.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 612 associations by consensus.

FCGR3B by CCDC168 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →