Across TCGA pan-cancer cohorts, CCDC167 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCDC167’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LSCC), where CCDC167 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC167 is over-expressed in tumor.
LSCC and COAD are the cancer types where CCDC167 tumor–normal differential expression is most reproducible.