CCDC166

Across TCGA cell cohorts, CCDC166 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,141 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC166-associated GO terms across cancer lineages are Detection of chemical stimulus involved in sensory perception of pain, Regulation of protein localization to nucleus, and Rhythmic process. Each is linked with CCDC166 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC166-to-partner and partner-to-CCDC166 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of chemical stimulus involved in sensory perception of pain grouped by CCDC166-low versus CCDC166-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC166→partner) and Y-score (partner→CCDC166) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Detection of chemical stimulus involved in sensory perception of pain →	+0.636	+0.014	.009	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to nucleus →	+0.062	+0.032	<.001	.002	3	5
OESOPHAGUS	Rhythmic process →	+0.042	+0.057	.007	.004	3	5
OESOPHAGUS	Protein deacetylation →	+0.092	+0.041	.003	.009	3	5
OVARY	Negative regulation of macroautophagy →	+0.060	+0.088	.004	.004	2	6
OVARY	Fatty acid transmembrane transport →	+0.089	+0.060	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

Detection of chemical stimulus involved in sensory perception of pain by CCDC166 expression — BONE

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