CCDC163

Across TCGA patient cohorts, CCDC163 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC163-associated genes across cancer lineages are Ku80, EGFR_pY1173, and MIG-6. Each is linked with CCDC163 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC163-to-partner and partner-to-CCDC163 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by CCDC163-low versus CCDC163-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC163→partner) and Y-score (partner→CCDC163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.293	+2.820	.043	.036	3	1
UCEC	EGFR_pY1173 →	+0.118	+2.833	.015	.035	2	1
UCEC	MIG-6 →	+0.164	+2.820	.007	.036	1	2
UCEC	CD20 →	+0.193	+2.827	.016	.035	2	1
UCEC	GATA3 →	+0.434	+2.820	<.001	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Ku80 by CCDC163 expression — UCEC

Explore this box plot interactively →