Across TCGA patient cohorts, CCDC160 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC160-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and A-Raf_pS299. Each is linked with CCDC160 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC160-to-partner and partner-to-CCDC160 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC160→partner) and Y-score (partner→CCDC160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.127	-1.794	<.001	.004	3	1
UCEC	EGFR_pY1068 →	-0.249	-2.169	.003	.003	3	1
UCEC	A-Raf_pS299 →	-0.140	-2.000	<.001	.009	3	1
UCEC	ERK2 →	+0.209	+3.700	.001	.001	3	1
UCEC	FoxM1 →	+0.247	+1.807	.005	.004	3	1
UCEC	GAPDH →	+0.364	+2.459	.046	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

CCDC160 survival (RNA) · tumor vs normal (RNA) · all CCDC160 data types