Across TCGA patient cohorts, CCDC159 mutation is significantly associated with the RNA expression of many other genes, with 665 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC159-associated genes across cancer lineages are GTF3C6P1, RNU6-1085P, and RNU2-28P. Each is linked with CCDC159 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC159-to-partner and partner-to-CCDC159 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC159→partner) and Y-score (partner→CCDC159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GTF3C6P1 →	+0.176	+5.017	.005	.009	3	2
UCEC	RNU6-1085P →	+0.255	+2.336	.001	.006	3	2
UCEC	RNU2-28P →	+0.258	+2.478	.008	<.001	3	2
UCEC	SYPL1P1 →	+0.107	+2.538	<.001	.003	3	2
UCEC	VTRNA2-2P →	+0.351	+2.274	.002	.002	3	2
LUSC	SS18L2P2 →	+0.305	+5.706	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 665 associations by consensus.

Exploration

CCDC159 survival (RNA) · tumor vs normal (RNA) · all CCDC159 data types