Across TCGA patient cohorts, CCDC159 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC159-associated genes across cancer lineages are FoxM1, mTOR_pS2448, and p38-MAPK_pT180_Y182. Each is linked with CCDC159 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC159-to-partner and partner-to-CCDC159 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC159→partner) and Y-score (partner→CCDC159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.262	+2.584	.030	.011	3	1
UCEC	mTOR_pS2448 →	-0.156	-2.986	.024	.035	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.449	-3.000	.032	.036	3	1
UCEC	PDCD4 →	-0.579	-3.169	.008	.018	3	1
UCEC	PKC-delta_pS664 →	-0.129	-2.312	.021	.034	3	1
UCEC	Shc_pY317 →	-0.222	-2.584	.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

CCDC159 survival (RNA) · tumor vs normal (RNA) · all CCDC159 data types