Across TCGA patient cohorts, CCDC157 protein abundance is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCDC157-associated genes across cancer lineages are GAPDH, NT5DC3, and EIF2B4. Each is linked with CCDC157 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC157-to-partner and partner-to-CCDC157 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC157→partner) and Y-score (partner→CCDC157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GAPDH →	-1.220	-0.906	.001	.002	3	1
LUAD	NT5DC3 →	-1.108	-0.906	<.001	.002	3	1
LUAD	EIF2B4 →	-0.575	-0.906	<.001	.002	3	1
LUAD	CBFA2T3 →	+0.476	+0.906	<.001	.002	3	1
LUAD	LDHA →	-0.925	-1.200	.006	.006	3	1
LUAD	NAT10 →	-0.631	-0.906	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

Exploration

CCDC157 survival (RNA) · tumor vs normal (RNA) · all CCDC157 data types