CCDC157

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC157 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC157-associated genes across cancer lineages are GATA3, ATM, and Cyclin-B1. Each is linked with CCDC157 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC157-to-partner and partner-to-CCDC157 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC157→partner) and Y-score (partner→CCDC157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGATA3 →+0.238+2.598.006.00632
UCECATM →-0.517-2.584.014.01132
SKCMCyclin-B1 →+0.705+3.012.001.01832
UCECeEF2 →+0.361+2.584.030.01131
UCECEGFR_pY1068 →-0.293-2.584.012.01131
UCECERK2 →+0.202+2.999.024.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration