Across TCGA cell cohorts, CCDC157 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCDC157-associated genes across cancer lineages are PVALB, PAX4, and TAS2R7. Each is linked with CCDC157 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC157-to-partner and partner-to-CCDC157 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC157→partner) and Y-score (partner→CCDC157) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PVALB →	+0.504	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	PAX4 →	+0.035	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.032	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	CRISP2 →	+0.182	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	USP26 →	+0.204	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	BSND →	+0.030	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

CCDC157 survival (RNA) · tumor vs normal (RNA) · all CCDC157 data types