Across TCGA patient cohorts, CCDC154 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CCDC154-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of actin nucleation, and Positive regulation of double-strand break repair. Each is linked with CCDC154 in more than 26 cancer types. Because this analysis shows association rather than direction, both CCDC154-to-partner and partner-to-CCDC154 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC154→partner) and Y-score (partner→CCDC154) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of DNA repair →	+0.051	+1.296	<.001	<.001	3	27
KIRC	Regulation of actin nucleation →	+0.045	+0.683	<.001	<.001	3	26
SCLC	Positive regulation of double-strand break repair →	+0.088	+1.659	<.001	<.001	3	26
SCLC	Protein deacetylation →	+0.097	+1.495	<.001	.002	2	27
ESCA	Spermidine metabolic process →	+0.057	+0.496	<.001	.001	3	26
SCLC	Obsolete histone deacetylation →	+0.123	+1.517	<.001	<.001	2	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Exploration

CCDC154 survival (RNA) · tumor vs normal (RNA) · all CCDC154 data types