Across TCGA cell cohorts, CCDC154 mutation is significantly associated with the RNA expression of many other genes, with 239 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC154-associated genes across cancer lineages are MYOD1, KRTAP1-4, and IL36A. Each is linked with CCDC154 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC154-to-partner and partner-to-CCDC154 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC154→partner) and Y-score (partner→CCDC154) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MYOD1 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	KRTAP1-4 →	+0.143	+4.906	<.001	.006	3	1
BREAST	IL36A →	+0.064	+5.169	<.001	.005	3	1
BREAST	DIRC1 →	+0.025	+5.169	<.001	.005	3	1
BREAST	C1orf185 →	+0.066	+5.781	<.001	.001	3	1
LARGE_INTESTINE	GCAT →	+1.306	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 239 associations by consensus.

Exploration

CCDC154 survival (RNA) · tumor vs normal (RNA) · all CCDC154 data types