CCDC150

Across TCGA patient cohorts, CCDC150 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC150-associated genes across cancer lineages are Annexin-1, eIF4E, and MEK1. Each is linked with CCDC150 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC150-to-partner and partner-to-CCDC150 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by CCDC150-low versus CCDC150-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC150→partner) and Y-score (partner→CCDC150) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.598	+2.522	<.001	<.001	3	3
UCEC	eIF4E →	+0.203	+2.000	.002	<.001	3	2
UCEC	MEK1 →	+0.454	+2.736	<.001	<.001	3	2
UCEC	p62 Lck ligand →	+0.279	+1.765	.008	.011	3	2
UCEC	Akt_pT308 →	+0.565	+2.321	.005	.005	3	2
UCEC	PCNA →	+0.154	+1.222	.028	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Annexin-1 by CCDC150 expression — UCEC

Explore this box plot interactively →