CCDC15

Across TCGA pan-cancer cohorts, CCDC15 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC15 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCDC15 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC15 expression acts as an unfavorable survival marker.

LUAD, COAD, and ESCA are the cancer types where CCDC15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.307	0.834	.001	13	view →
COAD	OS	Median	All	0.111	0.871	<.001	12	view →
ESCA	OS	Median	II,III,IV	0.130	0.687	<.001	9	view →
SKCM	OS	Median	All	0.645	0.870	<.001	7	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC15–LUAD (OS)

Open the LUAD breakdown →