CCDC149

Across TCGA patient cohorts, CCDC149 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,866 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCDC149-associated proteins across cancer lineages are CCDC149_S379, DDX21_S89, and CTBP1. Each is linked with CCDC149 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC149-to-partner and partner-to-CCDC149 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC149 versus CCDC149_S379 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC149→partner) and Y-score (partner→CCDC149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCDC149_S379 →	+1.013	+0.796	<.001	<.001	3	9
OV	DDX21_S89 →	-1.279	-0.557	.001	<.001	3	6
OV	CTBP1 →	+0.288	+0.430	<.001	<.001	3	6
BRCA	RSL1D1 →	-0.420	-0.449	.001	.001	3	5
BRCA	SEPTIN11 →	+0.262	+0.463	.002	<.001	3	5
CCRCC	CNRIP1 →	+0.443	+0.344	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,866 associations by consensus.

CCDC149 vs CCDC149_S379 — BRCA

Explore this scatter interactively →