CCDC149

Across TCGA patient cohorts, CCDC149 protein abundance is significantly associated with the RNA expression of many other genes, with 6,233 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC149-associated genes across cancer lineages are RAD51AP1, HROB, and TICRR. Each is linked with CCDC149 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC149-to-partner and partner-to-CCDC149 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC149 versus RAD51AP1 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC149→partner) and Y-score (partner→CCDC149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51AP1 →	-0.946	-0.331	.001	.001	3	4
BRCA	HROB →	-0.588	-0.360	<.001	<.001	3	4
UCEC	TICRR →	-0.870	-0.429	.002	<.001	3	4
BRCA	C9orf152 →	+1.354	+0.287	<.001	<.001	3	4
UCEC	PRR11 →	-1.105	-0.395	.001	<.001	3	4
LUAD	TRIP13 →	-0.724	-0.142	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,233 associations by consensus.

CCDC149 vs RAD51AP1 — UCEC

Explore this scatter interactively →