CCDC149

Across TCGA patient cohorts, CCDC149 mutation is significantly associated with the RNA expression of many other genes, with 3,376 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC149-associated genes across cancer lineages are RNU6-1254P, LINC01758, and RNU7-110P. Each is linked with CCDC149 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC149-to-partner and partner-to-CCDC149 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1254P grouped by CCDC149-low versus CCDC149-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC149→partner) and Y-score (partner→CCDC149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1254P →	+0.384	+3.799	<.001	.007	3	2
BLCA	LINC01758 →	+0.209	+4.112	<.001	.004	3	2
BLCA	RNU7-110P →	+0.873	+3.642	<.001	.009	3	2
UCEC	MCAT →	+0.432	+2.914	<.001	.001	3	2
UCEC	ADNP2 →	+0.579	+2.847	<.001	.001	3	2
UCEC	OIP5 →	+0.816	+2.343	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,376 associations by consensus.

RNU6-1254P by CCDC149 expression — BLCA

Explore this box plot interactively →