CCDC149

Across TCGA cell cohorts, CCDC149 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,515 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCDC149-associated GO terms across cancer lineages are Positive regulation of protein modification by small protein conjugation or removal, Endoplasmic reticulum unfolded protein response, and Positive regulation of intracellular transport. Each is linked with CCDC149 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC149-to-partner and partner-to-CCDC149 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein modification by small protein conjugation or removal grouped by CCDC149-low versus CCDC149-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC149→partner) and Y-score (partner→CCDC149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of protein modification by small protein conjugation or removal →	+0.060	+0.941	.001	<.001	3	12
STOMACH	Endoplasmic reticulum unfolded protein response →	+0.105	+1.479	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of intracellular transport →	+0.074	+1.344	<.001	<.001	3	12
OESOPHAGUS	ER-nucleus signaling pathway →	+0.115	+1.299	.002	<.001	3	12
OESOPHAGUS	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.123	+1.043	<.001	.003	3	12
OESOPHAGUS	Regulation of macroautophagy →	+0.082	+1.073	<.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,515 associations by consensus.

Positive regulation of protein modification by small protein conjugation or removal by CCDC149 expression — LUNG_SCLC

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