CCDC148

Across TCGA patient cohorts, CCDC148 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,803 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC148-associated proteins across cancer lineages are PKP4, PKP4_S382, and WDR54. Each is linked with CCDC148 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCDC148-to-partner and partner-to-CCDC148 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC148 versus PKP4 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC148→partner) and Y-score (partner→CCDC148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PKP4 →	+0.491	+0.483	<.001	<.001	3	8
UCEC	PKP4_S382 →	+0.511	+0.730	<.001	<.001	3	7
BRCA	WDR54 →	+0.368	+0.459	<.001	<.001	3	6
HNSC	DDAH1 →	+0.536	+0.586	<.001	<.001	3	6
BRCA	ARFGEF3 →	+0.610	+0.462	<.001	.001	3	5
BRCA	PKP4_S281 →	+0.700	+0.527	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,803 associations by consensus.

CCDC148 vs PKP4 — BRCA

Explore this scatter interactively →