CCDC148

Across TCGA patient cohorts, CCDC148 protein abundance is significantly associated with the RNA expression of many other genes, with 548 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCDC148-associated genes across cancer lineages are ASB2, SIRPB1, and PPP1R16B. Each is linked with CCDC148 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC148-to-partner and partner-to-CCDC148 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC148 versus ASB2 in LUAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC148→partner) and Y-score (partner→CCDC148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASB2 →	+0.501	+1.026	.006	.001	3	1
LUAD	SIRPB1 →	+0.544	+0.943	.002	.001	3	1
LUAD	PPP1R16B →	+0.719	+1.070	.004	.001	3	1
LUAD	HSF4 →	-0.766	-0.906	.003	.004	3	1
LUAD	NME3 →	-0.666	-0.889	.001	.001	3	1
LUAD	ZNF174 →	-0.370	-0.997	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 548 associations by consensus.

CCDC148 vs ASB2 — LUAD

Explore this scatter interactively →