CCDC148

Across TCGA cell cohorts, CCDC148 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,116 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC148-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with CCDC148 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC148-to-partner and partner-to-CCDC148 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CCDC148-low versus CCDC148-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC148→partner) and Y-score (partner→CCDC148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of myoblast fusion →	+0.075	+0.877	<.001	<.001	3	10
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.096	+1.046	<.001	.001	3	10
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.082	+1.001	<.001	<.001	3	10
STOMACH	Positive regulation of protein modification by small protein conjugation or removal →	+0.082	+0.523	<.001	.007	3	10
KIDNEY	Regulation of myoblast fusion →	+0.104	+1.128	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of organelle assembly →	+0.052	+1.303	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,116 associations by consensus.

Negative regulation of myoblast fusion by CCDC148 expression — KIDNEY

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