CCDC146

Across TCGA patient cohorts, CCDC146 protein abundance is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC146-associated genes across cancer lineages are KRT8P50, RN7SL217P, and MIR6859-3. Each is linked with CCDC146 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC146-to-partner and partner-to-CCDC146 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC146 versus KRT8P50 in UCEC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC146→partner) and Y-score (partner→CCDC146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRT8P50 →	+0.273	+1.176	<.001	.008	2	1
UCEC	RN7SL217P →	+0.323	+1.118	.001	.001	2	1
UCEC	MIR6859-3 →	+1.416	+1.117	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCDC146 vs KRT8P50 — UCEC

Explore this scatter interactively →