CCDC146

Across TCGA patient cohorts, CCDC146 protein abundance is significantly associated with the go_rna of many other GO terms, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC146-associated GO terms across cancer lineages are Response to Thyroglobulin triiodothyronine, Glucose catabolic process, and Positive regulation of endoplasmic reticulum unfolded protein response. Each is linked with CCDC146 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC146-to-partner and partner-to-CCDC146 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to Thyroglobulin triiodothyronine grouped by CCDC146-low versus CCDC146-high in UCEC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC146→partner) and Y-score (partner→CCDC146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Response to Thyroglobulin triiodothyronine →	+0.133	+0.206	.005	.004	3	1
UCEC	Glucose catabolic process →	+0.049	+0.203	.006	.004	2	1
UCEC	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.083	+0.186	.009	.002	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Response to Thyroglobulin triiodothyronine by CCDC146 expression — UCEC

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