CCDC144A

Across TCGA pan-cancer cohorts, CCDC144A Mutation is linked to patient survival in 12 of 34 cancer types, making it a survival-associated CCDC144A data layer compared with 21 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CCDC144A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC144A expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

BRCA, KIRC, and BLCA are the cancer types where CCDC144A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.336	0.581	<.001	32	view →
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
BLCA	DFS	Median	IV	0.090	0.469	.009	12	view →
LIHC	DFS	Median	All	0.197	0.447	.019	10	view →
UCEC	DFS	Median	All	0.947	0.825	.012	10	view →
COAD	OS	Median	All	0.190	0.674	.023	7	view →
PCPG	DFS	Median	All	0.094	0.768	.008	6	view →
LGG	DFS	Median	All	0.083	0.826	<.001	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	DFS	Median	III,IV	0.180	0.659	.006	5	view →
STAD	DFS	Median	II,III,IV	0.871	0.365	.037	4	view →
ESCA	DFS	Median	III,IV	0.100	0.425	.005	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

CCDC144A–BRCA (OS)

Open the BRCA breakdown →