CCDC144A

Across TCGA patient cohorts, CCDC144A mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC144A-associated genes across cancer lineages are PCNA, c-Met_pY1235, and GAPDH. Each is linked with CCDC144A in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC144A-to-partner and partner-to-CCDC144A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by CCDC144A-low versus CCDC144A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC144A→partner) and Y-score (partner→CCDC144A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.254	+3.999	<.001	<.001	3	4
UCEC	c-Met_pY1235 →	+0.042	+1.257	.049	.027	3	4
UCEC	GAPDH →	+0.515	+2.584	<.001	<.001	3	3
UCEC	ASNS →	+0.308	+1.289	.003	.021	3	3
UCEC	ATM →	-0.718	-2.459	<.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.672	+2.157	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

PCNA by CCDC144A expression — UCEC

Explore this box plot interactively →