CCDC142

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC142 mutation is significantly associated with the RNA expression of many other genes, with 3,156 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC142-associated genes across cancer lineages are LINC01203, TUBB8P4, and RNU6-377P. Each is linked with CCDC142 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC142-to-partner and partner-to-CCDC142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01203 grouped by CCDC142-low versus CCDC142-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC142→partner) and Y-score (partner→CCDC142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01203 →+0.918+2.236<.001.00833
SKCMTUBB8P4 →+0.020+3.005.004.00132
SKCMRNU6-377P →+0.542+3.208<.001<.00132
SKCMIGHVII-46-1 →+1.018+2.323<.001.00532
SKCMDEPDC1P1 →+0.031+2.328.004.00632
SKCMUBE2MP1 →+0.527+3.478.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,156 associations by consensus.

LINC01203 by CCDC142 expression — SKCM

Box plot of LINC01203 in CCDC142-low vs CCDC142-high samples in SKCM.

Explore this box plot interactively →

Exploration