CCDC142

Across TCGA cell cohorts, CCDC142 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC142-associated genes across cancer lineages are CT45A6, FGF6, and OR4D11. Each is linked with CCDC142 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC142-to-partner and partner-to-CCDC142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT45A6 grouped by CCDC142-low versus CCDC142-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC142→partner) and Y-score (partner→CCDC142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CT45A6 →	+0.022	+5.369	<.001	.004	3	1
LUNG_NSCLC_LUAD	FGF6 →	+0.225	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4D11 →	+0.023	+6.266	<.001	<.001	3	1
LARGE_INTESTINE	HTR1E →	+0.085	+3.930	<.001	.003	3	1
LARGE_INTESTINE	KCTD8 →	+0.149	+4.510	.009	.001	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.596	+4.196	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

CT45A6 by CCDC142 expression — SOFT_TISSUE

Explore this box plot interactively →