CCDC14

Across TCGA patient cohorts, CCDC14 protein abundance is significantly associated with the RNA expression of many other genes, with 2,014 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC14-associated genes across cancer lineages are CCNE1, UMPS, and NEK2. Each is linked with CCDC14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC14-to-partner and partner-to-CCDC14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC14 versus CCNE1 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC14→partner) and Y-score (partner→CCDC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCNE1 →	+0.803	+0.784	.002	.006	3	2
LSCC	UMPS →	+0.725	+0.580	<.001	<.001	3	2
UCEC	NEK2 →	+1.015	+0.434	.001	.002	3	2
UCEC	CENPF →	+1.025	+0.408	.001	.004	3	2
UCEC	FAAP24 →	+0.681	+0.542	.007	.009	3	2
UCEC	RUVBL1 →	+0.860	+0.541	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

CCDC14 vs CCNE1 — HNSC

Explore this scatter interactively →