CCDC14

Across TCGA cell cohorts, CCDC14 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCDC14-associated genes across cancer lineages are CRYGC, TSPY2, and UGT2A1. Each is linked with CCDC14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC14-to-partner and partner-to-CCDC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGC grouped by CCDC14-low versus CCDC14-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC14→partner) and Y-score (partner→CCDC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CRYGC →	+0.150	+4.087	<.001	.009	3	1
URINARY_TRACT	TSPY2 →	+0.192	+4.087	<.001	.009	3	1
URINARY_TRACT	UGT2A1 →	+0.011	+4.217	.002	.005	3	1
URINARY_TRACT	TGIF2LY →	+0.367	+4.217	.001	.005	3	1
URINARY_TRACT	PRAMEF7 →	+0.032	+4.087	<.001	.009	3	1
OVARY	PRR27 →	+0.110	+4.029	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

CRYGC by CCDC14 expression — URINARY_TRACT

Explore this box plot interactively →